Pain Management

Living with chronic pain can be incredibly challenging and impact many aspects of daily life. The physical discomfort can cause fatigue, difficulty sleeping, and reduced mobility, which can lead to social isolation, anxiety, and depression. Pain management aims to alleviate pain, improve physical function, and enhance quality of life for individuals experiencing pain.

A New Generation of Cold Water Dispersible and Soluble Ingredients

Boswellia LEO-HB® icon

Boswellia LEO-HB®

Caryophyllene LEO-HB® icon

Caryophyllene LEO-HB®



P.E.A. LEO-HB® icon


Piperine LEO-HB® icon

Piperine LEO-HB®

Boswellia has been traditionally used in Ayurvedic medicine for its anti-inflammatory and analgesic properties. The active components of Boswellia, called boswellic acids, have been found to inhibit the activity of enzymes called 5-lipoxygenase and cyclooxygenase, which are involved in the production of inflammatory molecules called leukotrienes and prostaglandins. By reducing the production of these inflammatory molecules, Boswellia can help reduce inflammation and pain in the body. In addition, Boswellia has been found to have antioxidant properties, which may also contribute to its anti-inflammatory effects. Overall, Boswellia has been shown to be a promising natural remedy for pain management, particularly in the treatment of osteoarthritis, rheumatoid arthritis, and other inflammatory conditions.*

Caryophyllene has been studied for its potential role in pain management. It is believed to have anti-inflammatory properties that may help to reduce pain and inflammation in the body. In addition, caryophyllene has been found to interact with the endocannabinoid system in the body, which is involved in regulating pain and inflammation. It is a selective agonist of the CB2 receptor, which is found primarily in immune cells and has been implicated in pain modulation.*

CBD has been shown to have potential pain-relieving properties, which may be due to its interaction with the body’s endocannabinoid system. This system is involved in regulating a variety of physiological processes, including pain sensation, mood, and inflammation. CBD interacts with two types of cannabinoid receptors in the body: CB1 and CB2 receptors. CB1 receptors are primarily located in the central nervous system, while CB2 receptors are mainly found in the immune system and peripheral tissues. When CBD binds to these receptors, it can help to modulate pain signals and reduce inflammation, which may contribute to its pain-relieving effects. In addition, CBD has been shown to inhibit the activity of an enzyme called fatty acid amide hydrolase (FAAH), which is involved in breaking down anandamide, an endocannabinoid that is involved in pain regulation. By inhibiting FAAH, CBD may increase the levels of anandamide in the body, which could further contribute to its pain-relieving effects.*

P.E.A. has been shown to reduce inflammation and pain by activating the body’s endocannabinoid system, which plays a role in regulating pain. Research has found that P.E.A. may be effective in managing a variety of pain conditions, including chronic neuropathic pain, sciatica, osteoarthritis, and chronic pelvic pain syndrome.*

Studies have shown that Piperine, a bioactive compound found in black pepper, has anti-inflammatory effects and can modulate pain signaling pathways in the body. Piperine has been found to reduce pain sensitivity and decrease levels of inflammatory cytokines in animal models of chronic pain. Additionally, piperine used in combinations with other medications or supplements has been found to enhance the pain-relieving effects.*