Sleep Health

A New Generation of Cold Water Dispersible and Soluble Ingredients

Sleep health refers to the quality and quantity of sleep that an individual experiences on a regular basis. It is a critical aspect of overall health and well-being, as it impacts various functions of the body and mind, such as cognitive performance, emotional regulation, immune system function, and cardiovascular health.

LEO-HB® Solutions for Sleep Health

Anandamide LEO-HB® icon

Anandamide
LEO-HB®

Caryophyllene LEO-HB® icon

Caryophyllene

LEO-HB®

CBD LEO-HB® Icon

CBD

LEO-HB®

P.E.A. LEO-HB® icon

P.E.A.

LEO-HB®

There is evidence to suggest that anandamide may play a role in regulating sleep and wake cycles. It has been shown to interact with the endocannabinoid system, which is involved in regulating various physiological processes, including sleep. Studies have found that anandamide levels fluctuate throughout the sleep-wake cycle, with levels increasing during sleep and decreasing during wakefulness. Additionally, a 2012 study published in the Journal of Psychiatric Research found that anandamide levels were significantly lower in people with insomnia compared to those without insomnia. The study authors hypothesized that this could be due to a dysregulation of the endocannabinoid system in people with sleep problems.

Caryophyllene has been shown to have anti-inflammatory and analgesic (pain-relieving) properties, which may help alleviate conditions that can interfere with sleep, such as chronic pain and inflammation.

Additionally, caryophyllene has been found to interact with the body’s endocannabinoid system, which plays a role in regulating sleep. It has been suggested that caryophyllene may help increase the levels of the endocannabinoid anandamide, which has been associated with improved sleep quality.

CBD interacts with the body’s endocannabinoid system, which plays a role in regulating sleep. It has been shown to modulate the activity of receptors in the endocannabinoid system, potentially promoting a state of relaxation that can help with falling asleep and staying asleep.

CBD has also been found to have anxiolytic (anti-anxiety) effects, which can be helpful for those who struggle with anxiety-related sleep disorders. Additionally, CBD has been suggested to have analgesic (pain-relieving) and anti-inflammatory properties, which may be useful for addressing chronic pain and inflammation that can interfere with sleep.

In studies involving both human and animal subjects, CBD has been found to increase total sleep time, decrease sleep latency (the amount of time it takes to fall asleep), and improve sleep quality.

PEA has been shown to interact with the endocannabinoid system, which plays a role in regulating various physiological processes, including sleep. Studies have found that PEA can bind to and activate cannabinoid receptors, similar to how cannabinoids like CBD and THC act.

 Some researchers found that administering PEA increased both non-rapid eye movement (NREM) and rapid eye movement (REM) sleep, and also improved sleep quality.

In addition to its potential effects on sleep, PEA has also been shown to have anxiolytic and antidepressant effects, which could also contribute to its potential therapeutic benefits for sleep disorders.

P.E.A. may  help to regulate sleep by modulating certain neurotransmitters in the brain. Specifically, P.E.A. has been shown to increase the activity of the GABA-A receptor, which is involved in the regulation of sleep-wake cycles.