- Gastrointestinal conditions*
- Blood sugar Management*
- Mood*
- Microbiota Modulation*
- Weight Management*
- Heart Health*
A New Generation of Cold Water Dispersible Ingredients
Description
- yellow to light orange powder, instantly Cold Water Dispersible, derived from an alkaloid found in the barks, leaves, twigs, rhizomes, roots, and/or stems of various plants, such as the barberry, Oregon grape, and tree turmeric.
- Traditionally used as an antimicrobial, antiprotozoal, and antidiarrheal agent in Ayurvedic medicine and traditional Chinese medicine.
- Taste: very bitter
Recommended Dosage: 375 mg to 750 mg daily
Clean Label Ingredients
Active Ingredient:
Berberine HCl
Other Ingredients:
Vegan formula: fiber and glycerin
Non-Vegan formula: hydrolyzed collagen and glycerin
LEO-HB® Technology
- LEO-HB® is an eco-friendly, state-of-the-art solid-solid technology that turns poorly soluble, bioactive ingredients with low bioavailability into free-flowing high performance powders that are instantly Cold Water Dispersible and/or Soluble.
- Contrary to many other technologies, LEO-HB® is a 100% natural, clean-label process, only uses non-GMO food-grade ingredients, NO solvents (NO P.E.G, NO Polysorbates) NO artificial emulsifiers, and has no negative impact on the digestive tract.
- Only Food-Grade, Non-GMO Clean Label Ingredients are used for every LEO-HB® ingredient: natural carrier (vegan or non-vegan), selected bioactive extract, natural glycerin (NO artificial emulsifiers, NO excipients, NO solvents)
- Final LEO-HB® ingredient powders:
- Are Cold Water Dispersible (80% min. vs. 0% for the unprocessed raw material)
- Offer maximum bioavailability from 3x to 20x+
- Offer customizable particle size
Dispersibility Assay
Left: Berberine LEO-HB®
Right: Berberine HCL
Solubility: Berberine LEO-HB® vs Native Berberine in acid medium
Protocol:
50 ml 0.1 N HCL solution
Ambient temperature
30-40mg of product
Berberine in Clinical Studies
Berberine is a natural plant compound that has been used for centuries in traditional medicine to treat a variety of health conditions. Today, it is gaining widespread attention for its potential to support overall health and well-being. Berberine has been extensively researched for its ability to lower blood sugar levels and improve insulin sensitivity, making it a powerful tool for managing diabetes and other blood sugar-related conditions. It has also been shown to have anti-inflammatory and antioxidant properties, which can help reduce the risk of chronic diseases and promote healthy aging. Additionally, berberine has antimicrobial effects, making it a useful supplement for supporting immune function and treating infections caused by bacteria, viruses, and fungi.
- Cardiovascular and Metabolic Properties
- Action on AMPK/ insulin secretion
- Microbiota modulation, digestive enzymes
- Neuroprotective Properties
- Cholinesterase inhibitor (MAO…)
- Anti-Inflammatory Properties
- Decrease in inflammatory markers (COX, PG…)
- Anti-Microbial Properties
- inhibition of bacterial protein synthesis
- Anti-Tumor Properties
- Inhibition of cellular proliferation
- Apoptosis regulation
Design Your Next Cutting-Edge Product with LEO-HB®
